Request for Proposals – Low Viscosity Solvent to Nebulise Nicotine for E-Cigarettes ArticlesBrowse More JobsBusiness By ogrepublic On Sep 25, 2016 0 Share Request Number REQ8322217 Due Date October 11, 2016 Author Stephen Clulow Trending Stories France gaz Predicts Natural Gas to Contribute 20% in French… PNC Forum 2024 Set To Discuss The Next Frontier For Nigerian… Request for Proposal Details Timeline Phase 1 – Shortlist solutions in Q4 2016 Phase 2 – Develop prototype within the next 6-12 months Phase 3 – Develop commercialization ready product within next 24 months Financials Flexible Partnering Opportunities. All financial terms are to be negotiated. For questions and comments, you are welcome to contact us at the SOLUTION PROVIDER HELP DESK: Email: phd@ninesigma.com Phone: +1-216-283-3901 RFP Title Low Viscosity Solvent to Nebulise Nicotine for E-Cigarettes RFP Description NineSigma, representing a leading international tobacco product manufacturer, invites proposals for alternative liquids or solvents for nebulizers that are low viscosity, can carry flavours and nicotine, and will deliver a good taste and smell experience to e-cigarette users. Background Nebulizers are used to break up a liquid into small droplets that can be inhaled. Water based liquids are currently used in nebulizers because liquids with high viscosity cannot be nebulized. However, water vapours do not carry nicotine to the lung and the sensorial experience of water based nicotine solutions is not as nice as the vegetable glycerin and propylene glycol liquid used in e-cigarettes. This project is to find liquids or solvents for nebulizers that combine a low viscosity, nicotine transport capabilities, and give a pleasurable taste and smell experience while inhaling aerosol from a nebulizer. Key Success Criteria Our client is seeking alternative liquids/solvents for nebulizers that combine: Low viscosity: Liquid or solvent can be nebulized Nicotine transport capabilities: Stabilizes nicotine in liquid aerosol phase by physical/chemical interactions such as high solubility or emulsion formation Liquid or emulsion to provide consistent vapor (amount and composition) during usage (≥ 200 puffs), after storage (≥ 6 months) Provides particles which have median of size in 0.03-0.5 micron diameter – preferably no particle over 1 micron range Good taste/sensorial experience. Liquid or solvent can transport flavors Taste and smell of liquid is acceptable – ideally no negative taste and smell, or at least tunable with flavoring technology. Safety: Safe to use Meets food applicable grade Anticipated Project Phases or Project Plan Phase 1 – Shortlist solutions in Q4 2016 Phase 2 – Develop prototype within the next 6-12 months Phase 3 – Develop a product ready for commercialization within next 24 months Possible Approaches Our client is open to all approaches that can fully or partially meet their requirements. “Systems” solutions including a device, in combination with a particular solvent are also in scope. Items to be submitted Appropriate responses will include only non-confidential information: A description of the liquid or solvent Evidence the liquid or solvent has low viscosity and can be nebulised Evidence the liquid or solvent could transport nicotine and flavours Evidence the liquid or solvent could give acceptable smell and taste Evidence the liquid or solvent is safe to use (e.g. non-toxic) An explanation of how you believe it could work in a nebuliser to deliver nicotine to the lung Status of technology and obstacles to be overcome (if required) Brief overview of the respondent(s) Overview of respondent(s) organization(s) A description of your / your organisations experience with liquid, solvents and nebulisation A description of your / your organisations experience with e-cigarettes (if any) Confirm you are open to engage in a feasibility study (when there are appropriate contracts) IP ownership / policy / freedom to operate Request Priority Normal Request Number REQ8322217 Due Date October 11, 2016 Author Stephen Clulow Online Application: To apply online, CLICK HERE FOR DETAILS Continue Reading E-CigarettesNineSigma ProposalsOil and Gas NewsProposal 0 Share